SLU-PP-332 – Research Compound
SLU-PP-332 is a low-molecular-weight synthetic compound functioning as a potent pan-agonist of estrogen-related receptors (ERRα, ERRβ, ERRγ), with highest affinity for ERRα (EC50 ≈ 98 nM). Originally developed at Saint Louis University, it has generated significant interest as a pharmacological exercise mimetic.
Research Context
Preclinical studies have demonstrated that SLU-PP-332 activates PGC-1α-dependent transcriptional programs associated with mitochondrial biogenesis, fatty acid oxidation, and increased energy expenditure — effects that parallel those observed with sustained aerobic exercise. In mouse models of metabolic syndrome, researchers observed decreased fat mass and improved insulin sensitivity without changes in food intake or physical activity.
Properties
- Class: Pan-ERR agonist / exercise mimetic
- CAS No.: 303760-60-3
- Molecular Weight: 290.32 g/mol
- Form: Supplied per specifications (oral or lyophilized depending on variant)
- Purity: ≥99% (third-party verified)
Storage & Handling
Store in a cool, dry place away from light. Follow batch-specific COA instructions for reconstitution and storage conditions.
Disclaimer: This product is strictly intended for in vitro laboratory research purposes only. Not for human or veterinary use.
